A02BB01 - Misoprostol |
Probably Not Porphyrinogenic |
PNP |
Rationale
Prostaglandin. Probably only insignificant hepatic exposure.
Chemical description
Tablets, 0.2-0.8 mg/d. Synthetic prostaglandin, which is inhibitor of gastric acid secretion. Mucosaprotective effect against ASA induced gastric lesions. Metabolized in several organs by beta-omega oxidation. Misoprostol and misoprostolic acid is excreted by the kidneys and faeces as various metabolites.
Ipnet drug reports
Uneventful use reported in 2 patients with acute porphyria.
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References
| # | Citation details | PubMed ID |
|---|---|---|
| Porphyria Drug Lists | ||
| 1. | French List
Centre Français des Porphyries
|
|
| 2. | South African List
Porphyria South Africa No longer maintained
|
|
Tradenames
Celprotec (nam) · Misoprostol Pfizer 
Cytotec 
Cytotec 
Cytotec 
Cytotec 
Cytotec 
Cytotec · Misoprostol 
Cytotec 
Cytotec · Misofar 
Cytotec · Misoprostol 
Cytotec 
Cytil · Miso-Care 
Avren · Cyotec Nasogastric · Cytotec · Rexol 
Cytotec 
Misoprostol 
Cytotec 
Cytotec 
Cytotec 
Cytotec 
Cytotec 
Cyprostol · Cytotec 
Misprostol