V08CA03 - Gadodiamide |
Not porphyrinogenic |
NP |
Mono.Rationale
Gadodiamide is excreted unchanged though the kidneys.
Mono.ChemicalDescription
Gadodiamide is a nonionic gadolinium chelate.
Mono.TherapeuticCharacteristics
Gadodiamide is used as a magnetic resonance contrast medium. It is administered intravenously. Nausea is a common adverse reaction of gadodiamide that can be confused with an acute porphyric attack.
Mono.HepaticExposure
Not relevant.
Mono.MetabolismAndPharmacokinetics
Gadodiamide is rapidly distributed into extracellular fluid. About 96% of a dose is excreted unchanged in the urine within 24 hours. No metabolites have been found.
Mono.SimilarDrugs
Mono.References
| # | Citation details | PubMed ID |
|---|---|---|
| Drug reference publications | ||
| 1. | Sweetman SC, editor. Martindale: The complete drug reference. Gadodiamide. Pharmaceutical Press 2009.
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| Summary of Product Characteristics | ||
| 2. | Norwegian medicines agency. Summary of Product Characteristics (SPC). Omniscan.
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Mono.Tradenames
Omniscan 
Omniscan 
Omniscan 
Omniscan 
Omniscan 
Omniscan 
Omniscan 
Omniscan 
Omniscan 
Omniscan 
Omniscan 
Gadolinium 
Omniscan 
Gadodiamida 
Gadodiamide