R03AC12 - Salmeterol |
Probably not porphyrinogenic |
PNP |
Mono.Rationale
Substrate for CYP 3A4. Probably insignificant metabolic load.
Mono.ChemicalDescription
Adrenergic administered in asthma in inhalation aerosol, 50 µg/dose. Gives rise only to very low plasma concentrations. Metabolized in the liver (CYP 3A4) producing several metabolites.
Mono.IpnetDrugReports
Uneventful use reported in 4 patients with acute porphyria.
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Mono.Tradenames