N02BF01 - Gabapentin |
Probably Not Porphyrinogenic |
PNP |
Rationale
Not metabolised.
Chemical description
Water-soluble methyl cyclohexane acetic acid structural analogue to GABA, used in additional treatment in all types of partial epilepsy. No first-pass metabolism, excreted in unchanged form in urine.
Personal communication
Andersson C, patient report: Tolerated (n=1).
Used in porphyria wards (Sweden).
Ipnet drug reports
Uneventful use reported in 25 patients with acute porphyria.
Similar drugs
Explore alternative drugs in similar therapeutic classes
References
| # | Citation details | PubMed ID |
|---|---|---|
| 1. | Gabapentin treatment of seizures in acute intermittent porphyria.
Tatum WO, Zachariah SB. Neurology. 1995 Jun; 45(6):1216-7.
|
7783893 |
| Porphyria Drug Lists | ||
| 2. | French List
Centre Français des Porphyries
|
|
| 3. | EPI List
European Porphyria Initiative No longer maintained
|
|
| 4. | South African List
Porphyria South Africa No longer maintained
|
|
Tradenames
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