Relatively small and water-soluble molecule (MW 179)
Mono.TherapeuticCharacteristics
Endogenous substance that possibly works by a positiv influence on cartilage metabolism. Common adverse reactions that can be mistaken for porphyria symptoms are dyspepsia, stomach ache, diarrhoea, constipation, nausea.
Mono.HepaticExposure
Significant
Mono.MetabolismAndPharmacokinetics
Metabolized mainly by the hexosamine-system and thereby independent of the cytopchrome P-450 system (1).
Mono.PreclinicalData
None
Mono.PersonalCommunication
None
Mono.PublishedExperience
None
Mono.IpnetDrugReports
Uneventful use reported in 28 patients with acute porphyria.