Acute Porphyria Drugs

J01DB01 - Cefalexin

Probably Not Porphyrinogenic
PNP

Rationale
Not metabolised. No data pointing to CYP interaction.
Chemical description
Perorally used cephalosporin (500mg x 2) antibiotic used in uncomplicated urinary tract infections, skin and soft tissue infections and in pharyngotonsillitis where penicillin V has shown to be without effect. No data pointing to CYP-interaction. Excreted in unchanged form by the kidneys.
Ipnet drug reports
Uneventful use reported in 8 patients with acute porphyria.
Similar drugs
Explore alternative drugs in similar therapeutic classes
  • J01D OTHER BETA-LACTAM ANTIBACTERIALS
  • J01DB First-Generation Cephalosporins
References
# Citation details PubMed ID
Porphyria Drug Lists
1. Australian List
Australian Porphyria Association No longer maintained
2. South African List
Porphyria South Africa No longer maintained
Tradenames

Auro-Cefalexin · Belex · Cefalexin 250 Alkem · Cefalexin 500 Alkem · Cephalexin Pharma-q · Ranceph Keforal Keforal Keforal Cefalexina · Kefloridina Forte Cefalexin · Pyassan Ceporex · Keforal Cefalexina · Keflex Cefalexin · Ceporex · Keflex Keflex Cefalexin · Keflex Keflex Cefaleksyna Afelex · Biocefal · Cefaflex · Cefalexina · Cefalexina a · Ceflax · Ceflaxilin · Ceprax · Cexgram -t · Cimotar · Cinfast · Crocefal · Efaltec · Efaltec Reconstruir a · Endamox · Enfarxin · Erocetin · Farvibact · Keflex · Lospor · Sinpox · Tiacef · Versaclox Cefalexin · Keflex Axcel Cephalexin · Cefalexin · Cephalex · Felexin · Sofilex · Uphalexin Cephalex · Cephalexin Keforal Keflex Keflex Kefalex · Kefexin Cefaleksin · Cefalexin · Palitrex Cefaleksin · Cefalexin Cefaleksin · Ceporex · Keflex · Oracef Cephalexin Cefalexine Cefalexina Cefalexin
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