D01AC03 - Econazole |
Probably not porphyrinogenic |
PNP |
Mono.Rationale
CYP-inducer. Probably insignificant systemic exposure.
Mono.ChemicalDescription
Broadspectrum imidazole antimycotic for dermatological use (gel/ creme/ liniment 1%). Inhibitor of CYPs 3A4 (potent), 2E1, 19 (aromatase), CYP-inducer. Probably only slight systemic absorbtion.
Mono.IpnetDrugReports
Uneventful use reported in 4 patients with acute porphyria.
Mono.SimilarDrugs
Mono.References
Mono.Tradenames
Pevaryl 
Pevaryl 
Ecorex · Ecosteril · Ganazolo · Ifenec · Pevaryl · Trosyd Ginecologico 
Pevaryl 
Ecostatin · Gyno-Pevaryl · Pevaryl 
Epi-Pevaryl · Pevaryl 
Pevaryl 
Pevaryl · Pevazol · Pevisone 
Dermazole · Ecostatin · Ecreme · Pevaryl · Pevaryl Anti-fungal · Pevaryl Healing 
Pevaryl 
Ecalin · Mitekol 
Pevaryl