Endogenous nucleoside. No relevant CYP metabolism.

Endogenous nucleoside.

Used to stop paroxysmal supraventricular tachycardia.

Adenosine is an endogenous nucleoside. Adenosine is rapidly taken up by most types of cells, including cellular elements of the blood (erythrocytes) and vascular endothelium, where it is rapidly degraded by deamination to inosine and subsequently to hypoxanthine. In addition, adenosine also undergoes phosphorylation to adenosine monophosphate (AMP) inside blood cells. Half-life in blood is less than 10 seconds. Non-CYP metabolism.

Adenosine monophosphate has been proposed and used as a therapeutic agent in the acute porphyrias in the late 60s (Wiontzek, bibliographic data only + Oaks)