Endogenous catecholamine. Non-CYP dependent metabolism. No data pointing to CYP-interaction.

Endogenous catecholamine.

Catecholamine used in asthma bronchiale, cardiac arrest, hypersensitivity reactions. Parenterally administered in 0.3-1 mg dose.

Epinephrine (adrenalin) is an endogenous compound. It is very rapidly inactivated by processes which include uptake into adrenergic neurones, diffusion, and enzymatic degradation in the liver and body tissues. Metabolism involves monoamine oxidase (MAO) and catechol-O-methyl transferase (COMT).

Uneventful use reported in 1 patient with acute porphyria.